Early-onset cancer is now considered a global health crisis. While rates of gastrointestinal cancer in populations 65 and older are declining, colorectal cancer is now the leading cause of cancer deaths in men under the age of 50 and the second among women of the same age. The question is why? Dr. Kimmie Ng, founding director of the Young-Onset Colorectal Cancer Center at the Dana-Farber Cancer Institute, joins The Excerpt to explain how the medical and research community is tackling this troubling development.